Chicago White Sox vs. Chicago Cubs: MLB Betting Odds and Picks

The Chicago White Sox (15-17) and Chicago Cubs (11-18) will open up a MLB interleague series at Wrigley Field Monday night, with the first pitch scheduled for 8:05 p.m. ET

Chicago White Sox vs. Chicago Cubs 

The Chicago Cubs have fared well against left-handed starters in recent games
The Chicago Cubs have fared well against left-handed starters in recent games

The Chicago White Sox snapped a four-game losing streak Sunday afternoon, as it picked up a 4-3 win over the Cleveland Indians as +138 road underdogs, while going UNDER the betting total for the fourth time in five contests.  The White Sox continue to be led by first baseman Jose Abreu offensively, as he leads the majors with 12 home runs and has driven in a AL-best 34 runs.  The franchise is 6-10 on the road this season, with the OVER going 9-6-1 in that situation.

White Sox starting pitcher Jose Quintana (1-2, 4.00 ERA) has watched the club drop his last three outings, but he didn’t earn a decision in a 4-3 home setback to the Detroit Tigers last time out, as he allowed three runs and eight hits over six innings of work.  The left-hander is 1-2 with a 5.00 ERA in three road appearances, with opposing hitters batting .304 against him.  Quintana allowed four runs over six innings in his only career start against the Cubs in 2013.

The Chicago Cubs had their three-game win streak snapped on ESPN’s Sunday Night Baseball, as it suffered a 5-4 loss to the St. Louis Cardinals as +119 home underdogs, while going OVER the betting total for the third time in four affairs.  The Cubs will likely have closer Hector Rondon unavailable for the series opener, as he worked his third consecutive game last night.  First baseman Anthony Rizzo will be leading the offense—hitting .396 in 16 home games.

Cubs starting pitcher Jeff Samardzija (0-3, 1.98 ERA) hasn’t earned a decision in his first six outings, as he looks to bounce back after suffering a 3-2 road defeat to the Cincinnati Reds last time out.  The right-hander is 0-2 with a 2.11 ERA in three home appearances—issuing seven walks and striking out 20 batters in 21.1 combined frames.    In five lifetime outings (two starts) against the White Sox, Samardzija has tallieda  1-2 record and 1.80 ERA.

Sports bettors will likely back the Cubs due to their 5-1 record in their last six interleague games versus left-handed starters.

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