MLB Picks: San Francisco Giants vs. Pittsburgh Pirates

The San Francisco Giants (33-30) and Pittsburgh Pirates (38-26) will continue a three-game National League series Wednesday night at PNC Park, with the first pitch scheduled for 7:05 p.m. ET

San Francisco Giants vs. Pittsburgh Pirates

San Francisco Giants SP Barry Zito is 0-3 with a 10.19 ERA in four road starts

San Francisco had its two-game winning streak snapped in a 8-2 setback to the Pittsburgh Pirates as +114 road underdogs Tuesday, while going OVER the betting total of 7.5. The Giants are now 12-19 away from AT&T Park this season, which is a surprise due to their 46-35 and 43-38 marks on the road the previous two seasons. San Francisco is 6-3 as road underdogs of +150 to +175 the last two-plus seasons, with the UNDER going 6-3 in that situation.

Giants starting pitcher Barry Zito (4-4, 4.06 ERA) suffered a 4-0 home loss to the Toronto Blue Jays last time out, as he allowed four runs and seven hits over six frames, while issuing three walks and failing to record a strikeout. The left-hander is 0-3 with a 10.19 ERA in four road starts, with opposing hitters batting .420 against him. In seven career games versus the Pirates, Zito has compiled a 2-3 record and 3.73 ERA, including a 1-2 mark and 4.41 ERA in three efforts at this ballpark.

Pittsburgh has won three of its last four games, but enters this affair with a 6-7 record against left-handed starters during the 2013 campaign. The Pirates are 14-8 against the Giants at this ballpark since 2006, which is important to consider when making your MLB picks Wednesday. Third baseman Pedro Alverez has been leading the way offensively, hitting .274 with eight home runs and 19 RBIs in his last 19 games. Pittsburgh is 22-11 in home games, with the UNDER going 21-11-1 in those 33 opportunities.

Pirates starting pitcher Francisco Liriano (4-2, 1.75 ERA) snapped a two-game losing streak with a 2-0 road victory over the Chicago Cubs last time out, as he allowed two hits over seven shutout frames. The left-hander is 2-1 with a 0.96 ERA in three home outings, with opposing hitters batting .174 against him. Liriano will be facing the Giants for the first time in his career.