NFL Week 16 Picks: San Francisco 49ers vs. Seattle Seahawks

San Francisco 49ers at Seattle Seahawks
Sunday, 12/23/12, 8:20 PM EST, TV:  NBC
Opening Point Spread:  Seattle -1
Current Betting Line:  Seattle -2.5
Opening Total:  40.5
Current Total:  40
Odds Courtesy of Bookmaker

Cardinals vs. 49ers NFL Preview

The San Francisco 49ers will need to run the football against the Seattle Seahawks Sunday night

San Francisco has won four of its last five games, including a 41-34 victory over the New England Patriots as four-point road underdogs last week, while going OVER the total for the fifth time in six contests.  “Our team has now hung in in a lot of big-time pressure games,” stated 49ers second-year head coach Jim Harbaugh.  The 49ers will put their perfect 5-0 record in primetime games on the line tonight, as they’ll be featured on NBC’s Sunday Night Football.  San Francisco is 2-0 SUATS as an underdog this season, which can’t be ignored when making your NFL picks against the spread in Week 16.

The 49ers have been very pleased with the play of quarterback Colin Kaepernick, who has posted a 104.4 passer rating since Week 11, which ranks third in the league among signal-callers in that span.  San Francisco has compiled a solid 11-4 record on the road under Harbaugh’s direction, which is tied with three others teams as the best such mark in the NFL in that span.

Seattle enters this division rivalry game on a three-game winning streak, as it comes off a 50-17 victory over the Buffalo Bills as 4.5-point road favorites, while going OVER the total in four consecutive games.  The Seahawks have lost four consecutive games in this series, including a 13-6 defeat as 7.5-point road underdogs on Oct. 18, as they were limited to 251 total yards of offense.  Seattle is 6-0 SUATS at home this season, but is 4-3 ATS as a favorite overall.

The Seahawks are second in the league in allowing just 219 points this season, which is just a point behind tonight’s opponent in that category.  Seattle will need to solidify its run defense in this affair, considering it has allowed an average of 133.5 yards on the ground in the last eight games.  Watch for some late-game scoring in this primetime affair, with the 49ers allowing 113 points in the fourth quarter, while the Seahawks have scored 85 in the final 15 minutes.

Sports bettors will likely back the Seahawks due to the home team covering five of the last seven meetings in this series.

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