NFL Thursday Night Picks: San Francisco 49ers vs. St. Louis Rams

San Francisco 49ers vs. St. Louis Rams
Thursday, 9/26/13, 8:25 PM EST
Opening Point Spread:  San Francisco -3
Current Betting Line:  San Francisco -3
Opening Total:  44
Current Total:  42
Odds Courtesy of Bookmaker

Rams 49ers NFL Preview

St. Louis Rams QB Sam Bradford is 2-0 at home against the San Francisco 49ers

San Francisco has dropped back-to-back games, including a 27-7 setback to the Indianapolis Colts as 10.5-point home favorites last Sunday, while going UNDER the betting total for a second consecutive contest.  “We’re working to improve the precision,” commented 49ers coach Jim Harbaugh.  “That’s where we’re at.”  49ers quarterback Colin Kaepernick desperately needs to regain his confidence, as he completed just 13 of 27 passes for 150 yards and an interception against the Colts.  San Francisco is 2-1 SU and 1-2 ATS as road favorite of three points or less the last two-plus season, which is important to consider when making your pro football picks in Week 4.

The 49ers got off to a tremendous start to their 2013 season with a victory over the Green Bay Packers, but they’ve been held to 461 total yards and picked up 18 penalties in their last two affairs.  San Francisco may have a hard time getting after the opposing signal-caller in this contest, as star outside linebacker Aldon Smith was placed on the reserve non-football injury list Monday as he entered rehab for substance abuse.  Fellow linebacker Patrick Wills and cornerback Nnamdi Asomugha are also dealing with nagging injuries.

St. Louis is set to open division play, as it also looks to snap a two-game losing streak, which includes a 31-7 blowout defeat to the Dallas Cowboys as 3.5-point road underdogs last Sunday.  “This is a defining moment for us right now,” commented Rams coach Jeff Fisher.  Rams quarterback Sam Bradford is off to a nice start this season, as he’s tied for first in the NFL with 88 completions, while sitting behind just six other throwers in passing for 891 yards.  St. Louis is 2-1 SUATS as home underdogs of three points or less the last two-plus seasons, with the UNDER going 3-0 in those opportunities.

The Rams will need to focus on stopping the 49ers’ rushing attack, as they allowed Cowboys running back DeMarco Murray to run for 175 yards and a touchdown on 26 carries in Week 3.  Bradford has enjoyed success in this series when playing at home—completing 71.1 percent of his passes in compiling a perfect 2-0 record.

Sports bettors will likely play the total, as the OVER is 8-2 in the 49ers’ last 10 games overall.

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